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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NKX2-1
All Species:
18.18
Human Site:
S327
Identified Species:
40
UniProt:
P43699
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P43699
NP_001073136.1
371
38596
S327
Q
P
G
S
A
G
Q
S
P
D
L
A
H
H
A
Chimpanzee
Pan troglodytes
XP_509911
401
41649
S357
Q
P
G
S
A
G
Q
S
P
D
L
A
H
H
A
Rhesus Macaque
Macaca mulatta
XP_001089890
371
38509
S327
Q
P
G
S
A
G
Q
S
P
D
L
A
H
H
A
Dog
Lupus familis
XP_849082
233
24205
E190
P
A
P
T
P
A
P
E
L
E
E
L
S
P
S
Cat
Felis silvestris
Mouse
Mus musculus
P50220
372
38552
S328
Q
P
G
S
A
G
Q
S
P
D
L
A
H
H
A
Rat
Rattus norvegicus
P23441
372
38536
S328
Q
P
G
S
A
G
Q
S
P
D
L
A
H
H
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90788
294
33054
V251
Y
N
C
S
Y
P
A
V
Q
P
V
Q
P
S
A
Frog
Xenopus laevis
P42587
196
22791
G153
V
P
V
L
V
R
D
G
K
P
C
H
T
L
K
Zebra Danio
Brachydanio rerio
Q90481
269
30288
A226
D
L
A
A
T
F
Q
A
G
I
P
F
S
A
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9NLC2
299
33058
V256
E
E
E
S
E
K
P
V
L
K
P
S
G
V
F
Sea Urchin
Strong. purpuratus
NP_999800
411
44821
V356
I
G
L
S
P
V
S
V
H
A
H
H
Q
H
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.7
99.1
40.7
N.A.
98.1
98.6
N.A.
N.A.
32
30.7
32.6
N.A.
N.A.
N.A.
26.6
38.4
Protein Similarity:
100
91.7
99.1
46.6
N.A.
98.1
98.6
N.A.
N.A.
43.4
40.4
43.4
N.A.
N.A.
N.A.
40.4
50.3
P-Site Identity:
100
100
100
0
N.A.
100
100
N.A.
N.A.
13.3
6.6
6.6
N.A.
N.A.
N.A.
6.6
13.3
P-Site Similarity:
100
100
100
20
N.A.
100
100
N.A.
N.A.
20
6.6
20
N.A.
N.A.
N.A.
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
10
10
46
10
10
10
0
10
0
46
0
10
55
% A
% Cys:
0
0
10
0
0
0
0
0
0
0
10
0
0
0
0
% C
% Asp:
10
0
0
0
0
0
10
0
0
46
0
0
0
0
0
% D
% Glu:
10
10
10
0
10
0
0
10
0
10
10
0
0
0
0
% E
% Phe:
0
0
0
0
0
10
0
0
0
0
0
10
0
0
10
% F
% Gly:
0
10
46
0
0
46
0
10
10
0
0
0
10
0
0
% G
% His:
0
0
0
0
0
0
0
0
10
0
10
19
46
55
0
% H
% Ile:
10
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
10
0
0
10
10
0
0
0
0
10
% K
% Leu:
0
10
10
10
0
0
0
0
19
0
46
10
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
10
55
10
0
19
10
19
0
46
19
19
0
10
10
10
% P
% Gln:
46
0
0
0
0
0
55
0
10
0
0
10
10
0
0
% Q
% Arg:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
73
0
0
10
46
0
0
0
10
19
10
10
% S
% Thr:
0
0
0
10
10
0
0
0
0
0
0
0
10
0
0
% T
% Val:
10
0
10
0
10
10
0
28
0
0
10
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
10
0
0
0
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _